I think if you "push" the spot prime, total prime and painting over spots repaired with quick dry (or any) drywall compound without waiting the required and re-coat time - I suspect (my observation only - I'm not a chemist......) that the "surface tension" caused from the shrinkage of  subsequent coats of paint will pull blisters in the weakened and softened mud, which hasn't had the chance to dry out properly between coats. Because of this "suspicion", I have implemented rule #2.


Rule #2: Prime all drywall compounds with drywall primer and wait the required amount of time before re-coating.



























The porosity of these primers I suspect, allows the compound to dry out faster by releasing the water (and any "out gassing" with hot mud) more readily through the porous films of these primers. After spot priming with the PVA primer (and allowing it to dry properly) then a tighter film primer such as the satin sheen universal primers can be used as a total surface primer before top coating or paperhanging.

Note: When doing drywall repair, there is no excuse for not removing the sanding dust. Vacuum, tack rag (use micro fiber type of tack rag - not the oil rag type) or dust off  the sanding dust. Don't add another variable to the equation. Yes, the primer might wet the dust - but it might not, so don't take a chance

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There is another reason which I believe causes paint blistering on hot compounds (actually over any type of joint compound). When you prime over any compound, you "re-wet" the compound and temporarily "weaken" or soften it. Just take a wet rag to some compound that you slopped on some hardware or counter top etc.. and it will easily dissolve away once wetted.
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Again this rule isn't rocket science, but if you follow it impeccably, you will save yourself a lot of grief. Let me expand on this rule a bit. I never use satin (sheen) latex paints or satin (sheen) latex primers over drywall compound. The PVA primers designed for drywall compounds are flat and breath better than satin sheen primers/paints.
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Quick Setting Drywall Compounds pt.2
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